|
Symbol Name ID |
Des
desmin MGI:94885 |
| Darker colors indicate more annotations |
| Human Phenotypes | Left atrial enlargement |
Right atrial enlargement |
Dilated cardiomyopathy |
Hypertrophic cardiomyopathy |
Restrictive cardiomyopathy |
Interstitial cardiac fibrosis |
Cardiomegaly |
Stroke |
Abnormal left ventricular function |
Reduced left ventricular ejection fraction |
Mitral regurgitation |
Tricuspid regurgitation |
Pulmonary venous hypertension |
Bradycardia |
Supraventricular arrhythmia |
Atrial fibrillation |
Third degree atrioventricular block |
Congestive heart failure |
Reduced systolic function |
Syncope |
| Disease(s) Associated with DES | ||||||||||||||||||||
| dilated cardiomyopathy 1I | ||||||||||||||||||||
| myofibrillar myopathy 1 | ||||||||||||||||||||
| restrictive cardiomyopathy |
| Mouse Phenotypes | abnormal aorta elastic fiber morphology |
abnormal vascular smooth muscle morphology |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
abnormal intercalated disk morphology |
decreased myocardial fiber number |
increased myocardial fiber size |
myocardial fiber degeneration |
abnormal ventricle papillary muscle morphology |
disorganized myocardium |
myocardium necrosis |
thin myocardium |
abnormal heart morphology |
abnormal interventricular septum morphology |
increased heart weight |
enlarged heart |
cardiac hypertrophy |
increased heart left ventricle weight |
increased heart left ventricle wall thickness |
dilated heart left ventricle |
abnormal heart right ventricle morphology |
dilated heart right ventricle |
abnormal epicardium morphology |
cardiac fibrosis |
cardiac interstitial fibrosis |
dilated cardiomyopathy |
dystrophic cardiac calcinosis |
abnormal cardiovascular system physiology |
decreased cardiac stroke volume |
hemorrhage |
decreased cardiac muscle contractility |
decreased ventricle muscle contractility |
abnormal cardiac muscle relaxation |
abnormal heart echocardiography feature |
decreased left ventricle developed pressure |
increased left ventricle diastolic pressure |
ventricular tachycardia |
irregular heartbeat |
atrial fibrillation |
ventricular premature beat |
abnormal impulse conducting system conduction |
atrioventricular block |
abnormal heart electrocardiography waveform feature |
prolonged HV interval |
abnormal P wave |
sinoatrial block |
abnormal myocardial fiber physiology |
cardiomyopathy |
congestive heart failure |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||
| Destm1.1Ccrs/Destm1.1Ccrs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Destm1Cap/Destm1Cap | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Destm1Cba/Destm1Cba | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Destm1Ltho/Destm1Ltho | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Destm1.1Ccrs/Des+ | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Myh6-Des*)641Rbns/0 | ||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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